Article: A population of gap junction-coupled neurons drives recurrent network activity in a developing visual circuit.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Liu Z; Ciarleglio CM; Hamodi AS; Aizenman CD; Pratt KG J. Neurophysiol., 2016
18β-GA, μm | ||||
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Control | 20 | 30 | 40 | |
n | 15 | 10 | 5 | 8 |
Membrane capacitance, pF | 13.28 ± 0.63 | 12.64 ± 1.14 | 12.56 ± 0.62 | 12.85 ± 0.64 |
Input resistance, GΩ | 1.00 ± 0.07 | 1.09 ± 0.09 | 1.00 ± 0.15 | 0.78 ± 0.1 |
Access resistance, mΩ | 38.57 ± 1.83 | 37.91 ± 4.04 | 37.8 ± 4.05 | 35.89 ± 5.08 |
Resting membrane potential, mV | -34.64 ± 1.61 | -30.8 ± 1.82 | -35.60 ± 2.16 | -30.88 ± 2.81 |
sEPSC frequency, events/s | 6.05 ± 1.00 | 2.83 ± 0.66 | 4.05 ± 0.77 | 3.91 ± 0.98 |
sEPSC Amplitude, pA | 6.42 ± 0.47 | 5.74 + 0.38 | 6.16 ± 0.61 | 5.74 ± 0.39 |
Maximum Na+, pA | 325.85 ± 29.77 | 338.2 ± 26.59 | 372.68 ± 43.95 | 358.2 ± 57.73 |
Maximum K+, pA | 425.47 ± 32.90 | 341.53 ± 31.68 | 333.89 ± 28.92 | 385.18 ± 50.74 |
Values are means ± SE; n, no. of neurons.
18β-GA, 18β-glycyrrhetinic acid; sEPSC, spontaneous excitatory postsynaptic currents.
The 20-μm concentration of 18β-GA significantly decreased the frequency of sEPSCs of DL neurons (P = 0.025). None of the other properties was significantly altered by 18β-GA.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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